The activity of the human immune system changes depending on the time of day. According to the conclusion of scientists from the University of Geneva (UNIGE) in Switzerland and the Ludwig-Maximilian University (LMU) in Germany, when vaccinating against coronavirus, the time of day at which the injection is given may matter.
The studies were carried out on mice. Scientists monitored dendritic cells that actively recognize antigens – specific fragments of pathogens. Fragments usually allow vaccines to “train” the immune system to fight the virus and fight it without getting infected.
Experiments on mice have shown that dendritic cells move most actively at the end of the resting stage of the body, before resuming activity. For mice, this is the day, and for the human body – early morning before waking up.
Scientists are confident that in this way the time of day must be taken into account during vaccination and during anticancer immunotherapy, as this can increase the effectiveness of the procedures.
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