The reason for the appearance of blood clots after vaccination against coronavirus with a drug from the American company Johnson & Johnson may be a rare immune response, which leads to the activation of platelets. This, according to CNN, said the head of one of the research centers of the US Food and Drug Administration (FDA), Peter Marks.
“We do not have an exact reason, but a possible reason is the mechanism of the adenoviral vector, which, in extremely rare cases, produces an immune response that leads to activation of platelets and the appearance of blood clots, similar to other vaccines,” he said.
According to the acting head of the FDA, Janet Woodcock, at the moment this is the “main version”, which is being tested by experts.
At the same time, the department recalled that cases of blood clots after the Johnson & Johnson vaccine are very rare, and a similar side effect was reported after the use of other drugs, in particular the vaccine of the British-Swedish company AstraZeneca.
Both of these vaccines – from Johnson & Johnson and AstraZeneca – are vector vaccines. They use adenovirus as a vector, or transport, to deliver part of the coronavirus to the human body. They differ, among other things, in that the Johnson & Johnson vaccine is based on a human adenovirus, and AstraZeneca has a chimpanzee adenovirus.
Peace against AstraZeneca
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FOLLOWING
The FDA began testing Johnson & Johnson's vaccine after six vaccinees developed blood clots. Symptoms appeared in women between the ages of 18 and 48: one of them died, the other was hospitalized in critical condition. Following the American regulator, the European one also began to check the safety of the vaccine.
Against the background of reports of cases of blood clots after the Johnson & Johnson vaccination, the US authorities recommended that vaccination with this drug be suspended. According to the FDA, about 6.8 million doses of the vaccine had been administered in the country by April 12. Later Johnson & Johnson also announced the suspension of the supply of its drug to Europe.
