Scientists at the Duke-NUS School of Medicine in Singapore have found that the presence of SARS-CoV-2-specific T cells in the body in the early stages of the disease can prevent complications. This is reported in an article published in the journal Cell Reports. This is summarized in a press release on MedicalXpress.
The researchers analyzed changes in virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infection from disease onset to recovery or death. It turned out that in patients with mild symptoms there is an early induction of T-cells secreting interferon-gamma.
The results indicate that the coronavirus vaccine is likely to be more effective if it promotes the overall induction of both antibodies and T cells specific to the coronavirus.
Earlier, experts from Boston University, together with specialists from the National Laboratory for New Infectious Diseases, found a mechanism for how COVID-19 affects the tissues of the respiratory organs already an hour after infection, which consists in the destruction of the nuclear membrane in cells.
